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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EP300
All Species:
12.12
Human Site:
T1012
Identified Species:
22.22
UniProt:
Q09472
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09472
NP_001420.2
2414
264161
T1012
C
K
M
E
S
T
E
T
E
E
R
S
T
E
L
Chimpanzee
Pan troglodytes
XP_515155
2411
263753
T1012
C
K
M
E
S
T
E
T
E
E
R
S
T
E
L
Rhesus Macaque
Macaca mulatta
XP_001102844
2414
264251
T1012
C
K
M
E
P
T
E
T
E
E
R
S
T
E
L
Dog
Lupus familis
XP_851777
2404
260682
V1013
Q
K
S
E
P
M
E
V
D
E
K
K
P
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
V1049
Q
K
S
E
P
M
E
V
E
E
K
K
P
E
V
Rat
Rattus norvegicus
XP_001076610
2413
263563
T1010
G
K
V
E
P
T
E
T
E
E
R
G
P
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233888
2444
267496
Q1026
C
K
P
D
P
M
E
Q
E
E
K
K
T
E
V
Frog
Xenopus laevis
NP_001088637
2428
264402
V1039
M
K
S
E
P
M
E
V
E
E
K
K
T
E
I
Zebra Danio
Brachydanio rerio
XP_001332718
2667
289125
D1021
G
P
M
E
T
A
S
D
E
D
K
K
P
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
G1613
M
E
I
K
T
E
D
G
L
D
G
E
V
K
I
Honey Bee
Apis mellifera
XP_001122031
2606
284119
E1235
N
K
M
E
P
M
E
E
G
S
S
E
S
I
I
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
E853
K
E
Q
Q
A
K
R
E
P
T
P
P
P
T
E
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
G1258
N
S
T
T
T
S
N
G
S
S
L
N
S
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
61
N.A.
58.6
94.1
N.A.
N.A.
85.1
60.4
57
N.A.
36.2
43
31.1
39.5
Protein Similarity:
100
99.7
99.5
72.4
N.A.
69.5
96.1
N.A.
N.A.
89.9
71
65.9
N.A.
46.6
54.9
45.6
51.5
P-Site Identity:
100
100
93.3
33.3
N.A.
40
66.6
N.A.
N.A.
46.6
46.6
26.6
N.A.
0
26.6
0
0
P-Site Similarity:
100
100
93.3
53.3
N.A.
53.3
73.3
N.A.
N.A.
66.6
60
53.3
N.A.
53.3
40
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
8
8
16
0
0
0
0
0
% D
% Glu:
0
16
0
70
0
8
70
16
62
62
0
16
0
70
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
0
0
0
16
8
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
31
% I
% Lys:
8
70
0
8
0
8
0
0
0
0
39
39
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
31
% L
% Met:
16
0
39
0
0
39
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% N
% Pro:
0
8
8
0
54
0
0
0
8
0
8
8
39
0
0
% P
% Gln:
16
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
31
0
0
0
8
% R
% Ser:
0
8
24
0
16
8
8
0
8
16
8
24
16
0
0
% S
% Thr:
0
0
8
8
24
31
0
31
0
8
0
0
39
16
0
% T
% Val:
0
0
8
0
0
0
0
24
0
0
0
0
8
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _